Prevalence of Helicobacter pylori among residents and their environments in the Nara prefecture, Japan

نویسندگان

چکیده

Chronic infection with Helicobacter pylori, specifically cagA-positive strains, is associated gastric cancer. Thus, measures to prevent H. pylori are required. This study was conducted clarify the prevalence of in community identify source and comprehensively assess risk infection. We collected 90 human faecal samples 73 environmental (water, vegetable, animal samples) from residents an area a high incidence cancer Japan. Polymerase chain reaction assay performed detect glmM housekeeping gene cagA virulence pylori. A questionnaire survey conducted, responses were analyzed statistically. The detected 18 (20%) obtained residents; among them, 33.3% (6/18), all who had undergone eradication therapy. not samples. However, contact dogs (OR 3.89, 95% CI 1.15–13.15, P < 0.05) higher odds for positivity survey. strains low. results suggest correlation between recurrent strains. Although genes living environments, association positive status revealed. Further investigations targeting community-dwelling healthy people their environments would be required control.

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ژورنال

عنوان ژورنال: Journal of Infection and Public Health

سال: 2021

ISSN: ['1876-035X', '1876-0341']

DOI: https://doi.org/10.1016/j.jiph.2020.11.018